Experimental model of asthma by toluene diisocyanate (TDI).
نویسندگان
چکیده
منابع مشابه
Role of intercellular adhesion molecule-1 in a murine model of toluene diisocyanate-induced asthma.
BACKGROUND Adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) are thought to contribute to the airway inflammation and airway hyper-responsiveness (AHR) of allergic asthma. Some differences from allergic asthma have been noted, including airway neutrophilia, and the involvement of ICAM-1 in toluene diisocyanate (TDI) asthma is currently unclear. OBJECTIVE We utilized mice l...
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The isocyanates are widely used as precursors of polyurethane products, as well as carbamate insecticides. Toluene 2,4-diisocyanate (TDI) is one of the most important commercially used isocyanates. Humans may be exposed to TDI by inhalation, ingestion, dermal and eye contact. TDI is a powerful irritant to the mucosal membranes of the gastrointestinal and respiratory tracts, eyes and the skin. P...
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ورودعنوان ژورنال:
- Bulletin of the Chest Disease Research Institute, Kyoto University
دوره 16 1-2 شماره
صفحات -
تاریخ انتشار 1983